Tilla Worgall is an expert in sphingolipid metabolism. She is a physician scientist and principle investigator of a basic research laboratory that focuses on sphingolipid metabolism. Her laboratory is equipped with high-pressure liquid chromatograph coupled to a mass spectrometer (HPLC-MS/MS) instrumentation required for analysis of nuclear sphingosine-1-phosphate and cellular sphingolipids.
She is also a member of the Institute of Human Nutrition.
Worgall TS. Lipid metabolism in cystic fibrosis. Curr Opin Clin Nutr Metab Care. 2009 Mar;12(2):105-9. Review.
Chang CL, Seo T, Matsuzaki M, Worgall TS, Deckelbaum RJ. n-3 fatty acids reduce arterial LDL-cholesterol delivery and arterial lipoprotein lipase levels and lipase distribution. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):555-61. Epub 2009 Feb 5.
Hamai H, Keyserman F, Quittell LM, Worgall TS. Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling. J Lipid Res. 2009 Jun;50(6):1101-8. Epub 2009 Jan 14.