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Ian Lipkin

John Snow Professor of Epidemiology; Professor of Neurology and Pathology and Cell Biology; Director, Center for Infection and Immunity
School: 
College of Physicians and Surgeons , Public Health
Department: 
Epidemiology Department, Neurology Department, Pathology, Center for Infection and Immunity, Epidemiology
Office: 
722 West 168th Street, Room 1703a
Email: 
wil2001@columbia.edu
Phone: 
212-342-9033
Fax: 
212-342-9044
Biography

W. Ian Lipkin, MD, is internationally recognized as an authority on the use of molecular methods for pathogen discovery. Dr. Lipkin has over 30 years of experience in diagnostics, microbial discovery and outbreak response, has mentored and trained more than 30 students and post-doctoral fellows and leads a team of over 65 investigators, post-doctoral fellows and research and support staff at MSPH. In the 1980s, Dr. Lipkin identified AIDS-associated immunological abnormalities and inflammatory neuropathy, which he showed could be treated with plasmapheresis, and demonstrated that early life exposure to viral infections affects neurotransmitter function. He was the first to use purely molecular methods to identify infectious agents, implicated West Nile virus as the cause of the encephalitis epidemic in New York in 1999, assisted the WHO and the Peoples Republic of China during the 2003 SARS outbreak, developed MassTag PCR and Greenechip technology and pioneered the use of high throughput sequencing in pathogen discovery. He and his team have discovered or characterized more than 500 infectious agents including Borna disease virus, West Nile virus, LuJo virus, human rhinovrirus C, piscine reovirus and canine hepacivirus. Dr. Lipkin has been featured by the New York Times, the Los Angeles Times, Discover Magazine, Nature Medicine, the History Channel, National Geographic, National Public Radio, Wired, and the Huffington Post. 

Research & Other Works
Article
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection
Article
Enterovirus 75 and aseptic meningitis, Spain, 2005
Article
Discovery and molecular characterization of West Nile virus NY 1999
Article
Pathogen discovery
Article
Induction of sterilizing immunity against West Nile Virus (WNV), by immunization with WNV-like particles produced in insect cells
Article
Molecular characterization of severe and mild cases of Influenza A (H1N1) 2009 strain from Argentina
Article
Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells
Article
A murine model for neuropsychiatric disorders associated with group A β-hemolytic streptococcal infection
Article
Induction of Toll-like receptor 3-mediated immunity during gestation inhibits cortical neurogenesis and causes behavioral disturbances
Article
Severe acute respiratory syndrome coronavirus persistence in Vero cells
Article
Genetic and epidemiological characterization of Stretch Lagoon orbivirus, a novel orbivirus isolated from Culex and Aedes mosquitoes in northern Australia
Article
Characterization of the major nuclear localization signal of the Borna disease virus phosphoprotein
Article
Genomic and phylogenetic characterization of Merino Walk virus, a novel arenavirus isolated in South Africa
Article
Epidemiologic investigation of immune-mediated polyradiculoneuropathy among abattoir workers exposed to porcine brain
Article
Neurotrophic factor expression after CNS viral injury produces enhanced sensitivity to psychostimulants : potential mechanism for addiction vulnerability
Article
Analysis of the medium (M) segment sequence of Guaroa virus and its comparison to other orthobunyaviruses
Article
Authentic Borna disease virus transcripts are spliced less efficiently than cDNA-derived viral RNAs
Article
Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda
Article
Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees
Article
Lack of association between measles virus vaccine and autism with enteropathy : a case-control study
Article
Global distribution of novel rhinovirus genotype
Article
Comprehensive viral oligonucleotide probe design using conserved protein regions
Article
Identification of GBV-D, a novel GB-like flavivirus from Old World frugivorous Bats (Pteropus giganteus) in Bangladesh
Article
RNA viruses in hymenopteran pollinators : evidence of inter-taxa virus transmission via pollen and potential impact on non-Apis hymenopteran species
Article
Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007
Article
Identification and characterization of a new bocavirus species in gorillas
Article
Greene SCPrimer : a rapid comprehensive tool for designing degenerate primers from multiple sequence alignments
Article
Heart and skeletal muscle inflammation of farmed salmon is associated with infection with a novel reovirus
Article
Nonparametric methods for the analysis of single-color pathogen microarrays
Article
Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from Southern Africa
Article
Real-time polymerase chain reaction for detecting SARS coronavirus, Beijing, 2003
Article
Nosocomial outbreak of novel arenavirus infection, Southern Africa
Article
Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses
Article
Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza
Article
A new arenavirus in a cluster of fatal transplant-associated diseases
Article
The relationships between West Nile and Kunjin viruses
Article
Detection of tick-borne pathogens by MassTag polymerase chain reaction
Article
Assessment of polymicrobial infections in ticks in New York State
Article
Panmicrobial oligonucleotide array for diagnosis of infectious diseases
Article
Cluster analysis of the origins of the new influenza A(H1N1) virus
Article
MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fevers
Article
Phylogenetic analysis of a human isolate from the 2000 Israel West Nile virus epidemic
Article
Astrovirus encephalitis in boy with X-linked agammaglobulinemia
Article
Diagnostic system for rapid and sensitive differential detection of pathogens
Article
Borna disease
Article
Novel Borna virus in psittacine birds with proventricular dilatation disease
Article
Novel picornavirus in turkey poults with hepatitis, California, USA
Article
Pandemic H1N1 Influenza Isolated from Free-Ranging Northern Elephant Seals in 2010 off the Central California Coast
Article
Pathosphere.org: pathogen detection and characterization through a web-based, open source informatics platform
Article
Analysis of Arbovirus Isolates from Australia Identifies Novel Bunyaviruses Including a Mapputta Group Virus from Western Australia That Links Gan Gan and Maprik Viruses
Article
Identification of a Novel Cetacean Polyomavirus from a Common Dolphin (Delphinus delphis) with Tracheobronchitis
Article
Novel Coronavirus and Astrovirus in Delaware Bay Shorebirds
Article
Air Travel Is Associated with Intracontinental Spread of Dengue Virus Serotypes 1–3 in Brazil
Article
Israeli Acute Paralysis Virus: Epidemiology, Pathogenesis and Implications for Honey Bee Health
Article
Distinct plasma immune signatures in ME/CFS are present early in the course of illness
Article
Adenovirus and Herpesvirus Diversity in Free Ranging Great Apes in the Sangha Region of the Republic of Congo
Article
Detailed Analysis of the African Green Monkey Model of Nipah Virus Disease
Article
Long-term storage of blood RNA collected in RNA stabilizing Tempus tubes in a large biobank – evaluation of RNA quality and stability
Article
Identification of a novel nidovirus in an outbreak of fatal respiratory disease in ball pythons (Python regius)
Article
Genome characterization of Long Island tick rhabdovirus, a new virus identified in Amblyomma americanum ticks
Article
A staged strategy for pathogen surveillance and discovery
Article
Nonparametric methods for the analysis of single-color pathogen microarrays
Article
Centroid based clustering of high throughput sequencing reads based on n-mer counts
Article
Characterization of Farmington virus, a novel virus from birds that is distantly related to members of the family Rhabdoviridae
Article
Longitudinal molecular microbial analysis of influenza-like illness in New York City, may 2009 through may 2010
Article
Human blood RNA stabilization in samples collected and transported for a large biobank
Article
A Strategy To Estimate Unknown Viral Diversity in Mammals
Article
Host–rabies virus protein–protein interactions as druggable antiviral targets
Article
Identification of Rodent Homologs of Hepatitis C Virus and Pegiviruses
 
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