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David Jonathan Brenner

Higgins Professor of Radiation Biophysics (in Radiation Oncology) and of Environmental Health Sciences; Director, Center for Radiological Research
School: 
Public Health
Department: 
Environmental Health Sciences, Radiation Oncology Department
Office: 
630 West 168th Street New York, NY 10032
Email: 
djb3@cumc.columbia.edu
Phone: 
212-305-5660
Fax: 
212 305-3229
Appointments
  • Director, Radiological Research Accelerator Facility
Biography

Dr. Brenner focuses on developing mechanistic models for the effects of ionizing radiation on living systems, both at the chromosomal and the animal (or human) levels. He divides his research time roughly equally between the effects of high doses of ionizing radiation (relating to radiation therapy) and the effects of low doses of radiation (relating to medical, environmental and occupational exposures).

At the chromosomal level, he has focused on the mechanisms of radiation-induced chromosome aberrations, and the potential of chromosome aberrations for use as biomarkers for past exposure to different types of radiations.

In the field of medical imaging, he has focused on the risk / benefit balance of the higher-dose imaging techniques, particularly computed tomography (CT).

In the field of radiotherapy, he has focused on optimizing fractionation schemes for different tumor types, to maximize tumor killing and minimize serious side effects; this includes modeling the mechanisms of radiotherapy-induced second cancers, with the goal of reducing second cancer risks.

Environmentally, he has focused on the biological effects of radon, both at the chromosomal and the human levels.

Research & Other Works
Article
Comparing proxy and model estimates of hydroclimate variability and change over the Common Era
Article
Commentary on the Syria case: Climate as a contributing factor
Article
Winter storm intensity, hazards, and property losses in the New York tristate area
Article
Understanding Pacific Ocean influence on interannual precipitation variability in the Sahel
Article
Mediterranean climate future: an insightful look into the Basin's precipitation response to greenhouse gas forcing
Article
HITS: Hurricane Intensity and Track Simulator with North Atlantic Ocean Applications for Risk Assessment
Article
Distinguishing the Roles of Natural and Anthropogenically Forced Decadal Climate Variability: Implications for Prediction
Article
Cross–Time Scale Interactions and Rainfall Extreme Events in Southeastern South America for the Austral Summer. Part I: Potential Predictors
Article
Old World megadroughts and pluvials during the Common Era
Article
Dead Sea drawdown and monsoonal impacts in the Levant during the last interglacial
Article
Hydroclimate Variability and Change in the Prairie Pothole Region, the “Duck Factory” of North America
Article
Human adaptation strategies to abrupt climate change in Puerto Rico ca. 3.5 ka
Article
The paths of extratropical cyclones associated with wintertime high wind events in the Northeast United States
Article
Persistent drying in the tropics linked to natural forcing
Article
The middle Holocene climatic records from Arabia: Reassessing lacustrine environments, shift of ITCZ in Arabian Sea, and impacts of the southwest Indian and African monsoons
Article
Natural and Forced North Atlantic Hurricane Potential Intensity Change in CMIP5 Models
Article
Influence of local and remote SST on North Atlantic tropical cyclone potential intensity
Article
Climate change in the Fertile Crescent and implications of the recent Syrian drought
Article
Moisture budget analysis of SST-driven decadal Sahel precipitation variability in the twentieth century
Article
Dynamical Structure of Extreme Floods in the U.S. Midwest and the United Kingdom
Article
Have Aerosols Caused the Observed Atlantic Multidecadal Variability?
Article
Coupled climate model simulations of Mediterranean winter cyclones and large-scale flow patterns
Article
Mediterranean precipitation climatology, seasonal cycle, and trend as simulated by CMIP5
Article
North Atlantic influence on 19th–20th century rainfall in the Dead Sea watershed, teleconnections with the Sahel, and implication for Holocene climate fluctuations
Article
Low-frequency climate variability in the Atlantic basin during the 20th century
Article
The 1960s Drought and the Subsequent Shift to a Wetter Climate in the Catskill Mountains Region of the New York City Watershed
Article
A verification framework for interannual-to-decadal predictions experiments
Article
Atlantic SST gradient and the influence of ENSO
Article
The Physical Basis for Predicting Atlantic Sector Seasonal-to-Interannual Climate Variability
Article
Hindcasts of Tropical Atlantic SST Gradient and South American Precipitation: The Influences of the ENSO Forcing and the Atlantic Preconditioning
Article
Variation of the North Atlantic subtropical high western ridge and its implication to Southeastern US summer precipitation
Article
Comparing Twentieth- and Twenty-First-Century Patterns of Interannual Precipitation Variability over the Western United States and Northern Mexico
Article
The relative contributions of radiative forcing and internal climate variability to the late 20th Century winter drying of the Mediterranean region
Article
Classifying North Atlantic Tropical Cyclone Tracks by Mass Moments
Article
Robust features of Atlantic multi-decadal variability and its climate impacts
Article
Northern Hemisphere winter snow anomalies: ENSO, NAO and the winter of 2009/10
Article
Tropical Oceanic Causes of Interannual to Multidecadal Precipitation Variability in Southeast South America over the Past Century
Article
Mechanisms of Tropical Atlantic SST Influence on North American Precipitation Variability
 
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