MSD-Thailand, an affiliate of Merck & Co., funded an ambitious science education program for lower secondary schools in southern Thailand from 2007-2012. The program known as the Inquiry Based Science and Technology Education Program (IN-STEP), was a public-private partnership among Kenan Institute Asia, the Ministry of Education, the Institute for the Promotion of Teaching Science & Technology, the Merck Institute for Science Education, and the Consortium for Policy Research in Education (CPRE) at Teachers College (TC). The program, over five years, trained educators to use guided investigations in the teaching of key concepts in the biological, physical, and earth sciences in grades 7, 8, and 9. The initiative also included activities such as annual science days and science camps to spark student and community interest in science. CPRE-TC lead the design and evaluation of IN-STEP, provided training for Thai evaluators, and assisted with training for mentors and school principals. Planning is underway to build on this work and begin a new set of programs.